Hyaluronic acid (HA), is a kind of acid mucopolysaccharide, which widely exists in animal organs and tissues, such as human placenta umbilical cord, cockscomb, ox eye and skin tissue. At present, the hyaluronic acid on the market is mainly extracted by fermentation biochemical technology. Hyaluronic acid, with its unique molecular structure and physical and chemical properties, shows many important physiological functions in the body, such as diffusion and operation of water and electrolyte, promoting wound healing and so on. In addition, hyaluronic acid has a special function of keeping water, which is the best moisturizing substance found in nature at present. It is called an ideal natural moisturizing factor.